Category Archives: McGill NMR Lab

Protein sequence conservation can be a valuable tool to assess functional regions of a protein. But sequence information can be complemented by the tridimensional structure of the protein of interest to give new insights on the structure-function relationship. Protein sequence … Continue reading →

Organism Length Sequence Accession # Blast Anemia Phyllitidis 638 MPALASALAS ASPEEQRVML GEQLYPLVDR LEH–DHAGK VTGMLLEMDQ PEVLHLIDLL RQLKAKVAEA MDVL CAA81127 A.Thaliana 668 ISKLASDLAL ASPDKHPRML GDHLYPLVEQ QEP–ANAAK VTGMLLEMDQ AEILHLLESP EALKAKVSEA LDVL AAF43230 Bos Taurus 636 EPLTASMLAS APPQEQKQML GERLFPLIQA MHP–TLAGK ITGMLLEIDN SELLHMLESP ESLRSKVDEA VAVL … Continue reading →

Our interests are centered on the application of Nuclear Magnetic Resonance (NMR) spectroscopy to the study of protein and nucleic acid structures. Previous structures included a peptide binding domain (PDZ domain) involved in signal transduction and a protein homeodomain (PBX) … Continue reading →